The Histology Core is part of the Knowledge Enterprise Biosciences division and is housed within the Regenerative Medicine and Flow Cytometry space on the ASU Tempe campus in ISTB1. The HistoCore provides histology services for basic science (non-clinical) research. Services include paraffin and frozen tissue processing, demineralization, sectioning, staining, labeling and imaging.

The ASU Genomics Facility offers sequencing services and expertise for both traditional and next-generation applications. In addition to the actual sequencing, the core provides a myriad of library preparation options for a variety of sample types and experimental requirements, ranging from single-cell RNA sequencing to microbial metagenomic sequencing.

The Regenerative Medicine Core offers cell culture instrumentation, support and services to ASU researchers and the surrounding scientific community. Located in the Interdisciplinary Science and Technology Building I, it uniquely combines instruments from the Flow Cytometry and Advanced Light Microscopy facilities to provide all the tools and technologies needed to conduct tissue, cell and stem cell culture-based research. The Histology Suite offers comprehensive services for researchers. These include sample processing with both formalin-fixed paraffin-embedded (FFPE) and frozen techniques, sectioning for FFPE and frozen samples, as well as various staining methods. The Core specializes in advanced techniques such as Immunohistochemistry (IHC), Immunocytochemistry (ICC), and Immunofluorescence (IF). Additionally, they provide essential support services like cassette and slide printing, high-resolution whole slide scanning and detailed image analysis. To ensure researchers can fully leverage these facilities, the Core also offers expert consultation and training sessions.

The Mass Spectrometry Facility provides mass spectrometry analysis to research groups at ASU and outside organizations in a wide array of research areas such as environmental, clinical, pharmaceutical, chemical, and biological. Researchers may utilize walk up use instruments as well as a large number of services performed on behalf of researchers by core facility staff.

A joint effort between the Barrow Neurological Institute and Arizona State University, the Barrow-ASU Center for Preclinical Imaging provides state-of-the-art imaging tools and expertise for researchers in the Phoenix area and endeavors to advance biosciences across Arizona.

The MRRC offers several nuclear magnetic resonance (NMR) spectrometers for elucidating structure, dynamics and behavior of proteins, biopolymers, pharmaceutical compounds and various organic/inorganic materials in solid or liquid states. Special modalities also enable micro-MRI, dedicated diffusion and ultra-high sensitivity studies. We offer complete automation of data collection for routine liquids NMR on multiple instruments.

The Flow Cytometry Facility, located within the Biodesign Institute, offers cell sorting (FACS), cell analysis, and applications support (panel design, wet lab help and data analysis) to researchers and students at ASU as well as the scientific community in the Phoenix metropolitan area.

The Advanced Light Microscopy Facility houses state-of-the-art research tools enabling observation of cellular structures and cellular processes in real time. Available imaging modalities include: widefield, fluorescent lifetime microscopy (FLIM), fluorescence, laser scanning confocal, light-sheet, total internal reflection fluorescence (TIRF), and super-resolution structured illumination microscopy (SIM).

The Bioinformatics Facility includes three components: routine data-analysis services, research-oriented collaborations and targeted training. Centralized high-end computation facilities and experienced bioinformaticians are accessible to investigators who are challenged by the large volume and increased complexity of omics data. Workshops focusing on various aspects of bioinformatics and biostatistics are also offered.

UFL specializes in the development and application of time-resolved laser spectroscopy for chemical, biological and materials research. Pulsed and CW lasers, transient absorption spectrometers, single-molecule microscopy, time-correlated single-photon counting and streak camera fluorescence setups enable characterization of various materials and chemical processes with incredible temporal and spatial resolution.

The DNA Shared Resource Facility houses instrumentation for characterization of DNA and RNA. This instrumentation includes devices for PCR including rtPCR, DNA genotyping, DNA sequencing, determination of quality and quantity of DNA and RNA preparations as well as other instrumentation useful in handling DNA and RNA.