The facilities within the Biosciences Core offer services and tools spanning genomics, histology, mass spectrometry, flow cytometry, advanced light microscopy, bioinformatics and more.
Histology Facility
The Histology Facility is part of the Knowledge Enterprise Biosciences division and is housed within the Regenerative Medicine and Flow Cytometry space on the ASU Tempe campus. The Histology Facility provides histology services for basic science (non-clinical) research. Services include paraffin and frozen tissue processing, demineralization, sectioning, staining, labeling and imaging.
Desert Southwest Genomics Center
The ASU Desert Southwest Genomics Center offers sequencing services and expertise for both traditional and next-generation applications. In addition to the actual sequencing, the core provides a myriad of library preparation options for a variety of sample types and experimental requirements, ranging from single-cell RNA sequencing to microbial metagenomic sequencing.
Regenerative Medicine
The Regenerative Medicine Core offers cell culture instrumentation, support and services to ASU researchers and the surrounding scientific community. Located on the ASU Tempe campus, it uniquely combines instruments from the Flow Cytometry and Advanced Light Microscopy facilities to provide all the tools and technologies needed to conduct tissue, cell and stem cell culture-based research.
Mass Spectrometry Facility
The Mass Spectrometry Facility provides mass spectrometry analysis to research groups at ASU and outside organizations in a wide array of research areas such as environmental, clinical, pharmaceutical, chemical, and biological. Researchers may use instruments on a walk-up basis or request services provided by core facility staff.
Preclinical Imaging
A joint effort between the Barrow Neurological Institute and Arizona State University, the Barrow-ASU Center for Preclinical Imaging provides state-of-the-art imaging tools and expertise for researchers in the Phoenix area and endeavors to advance biosciences across Arizona.
Magnetic Resonance Research Center
The MRRC offers several nuclear magnetic resonance (NMR) spectrometers for elucidating structure, dynamics and behavior of proteins, biopolymers, pharmaceutical compounds and various organic/inorganic materials in solid or liquid states. Special modalities also enable micro-MRI, dedicated diffusion and ultra-high sensitivity studies.
Flow Cytometry Facility
The Flow Cytometry Facility, located within the Biodesign Institute, offers cell sorting (FACS), cell analysis, and applications support (panel design, wet lab help and data analysis) to researchers and students at ASU as well as the scientific community in the Phoenix metropolitan area.
Advanced Light Microscopy Facility
The Advanced Light Microscopy Facility houses state-of-the-art research tools enabling observation of cellular structures and processes in real time. Available imaging modalities include widefield, fluorescent lifetime microscopy (FLIM), fluorescence, laser scanning confocal, light-sheet, total internal reflection fluorescence (TIRF) and super-resolution structured illumination microscopy (SIM).
Bioinformatics Facility
The Bioinformatics Facility includes three components: routine data-analysis services, research-oriented collaborations and targeted training. Centralized high-end computation facilities and experienced bioinformaticians are accessible to investigators who are challenged by the large volume and increased complexity of omics data. Workshops focusing on various aspects of bioinformatics and biostatistics are also offered.
Ultrafast Laser Facility
UFL specializes in the development and application of time-resolved laser spectroscopy for chemical, biological and materials research. Pulsed and CW lasers, transient absorption spectrometers, single-molecule microscopy, time-correlated single-photon counting and streak camera fluorescence setups enable characterization of various materials and chemical processes with incredible temporal and spatial resolution.
DNA Shared Resource Facility
The DNA Shared Resource Facility houses instrumentation for characterization of DNA and RNA. This instrumentation includes devices for PCR including rtPCR, DNA genotyping, DNA sequencing, determination of quality and quantity of DNA and RNA preparations as well as other instrumentation useful in handling DNA and RNA.