Capabilities

Bioinformatics support for omics data analysis

We are experienced in analyzing genomic, transcriptomic and metagenomic data. Our previous and current projects, primarily centered on short-read sequencing, include studies using techniques such as whole genome sequencing (WGS), ITS/16S/18S amplicon sequencing, transcriptome assembly and differential gene expression with RNA sequencing, whole genome metagenomics/metatranscriptomics, and single-cell and spatial sequencing. Additionally, we have experience working with IsoSeq and 16S metagenomics data from PacBio long-read sequencing. Bioinformatics Facility scientists can help investigators with omics data analysis using available software and can also develop customized tools.

Project design and data analysis consultation

Consultations are available upon request or during office hours. Coordinated project design consultation and data analysis support are available with the Desert Southwest Genome Center.

Bioinformatics support is available for both basic research and clinical research. The core uses and can provide assistance with open-source bioinformatics analysis software and develops analysis pipelines for diverse data types. Core scientists also can help researchers integrate diverse data sets, such as genomics, proteomics, metabolomics and imaging information.

Service activities

• Consulting on experimental design, sequencing and analysis goals; and results interpretation
• Support letters to secure research funding
• Figures and written materials (e.g., for proposals and manuscripts) support
• Differential gene expression analysis in an organism or host / pathogen system
• Novel transcript / isoform identification with PacBio long reads
• Bacterial genome de novo assembly and annotation
• 16S / 18S / ITS rRNA microbiome characterization
• Whole genome / transcriptome metagenomics and metatranscriptomics
• Whole genome re-sequencing and variant calling
• 10X single-cell and spatial sequencing analysis
• Custom analysis and workflow development for unique projects
• Any other bioinformatics support for omics/NGS data

Collaborations

The Bioinformatics Facility can participate in your projects via research-oriented collaborations. We apply state-of-the-art computational approaches and develop novel methods to accelerate biological discoveries, offering particular expertise in metagenomics / metatranscriptomics and different permutations of RNA sequencing. 

We offer project-based collaborations funded through either joint research grants or fee-for-services. We welcome new collaborations and can work with you to apply for joint funding. The facility provides collaborative support for large scale multidisciplinary research projects in close coordination with other ASU core facilities including genomics, imaging and mass spectrometry facilities.